A healthy immune system is the best defense against Coronavirus. Keeping your blood pressure at a normal level of between 90/50 to 120/80, is crucial to longevity. In four of the five volunteers, both systolic and diastolic blood pressure dropped. Nutrition 2003;19:261–4. Even though I am in pretty good shape – I workout every day and eat a healthy diet, I know that I must be vigilant if I want my later years to be as healthy as my younger ones. But what if there was a natural alternative, which could safely do the job of most of the above pharmaceuticals? By reducing the stickiness of arterial plaque, this enzyme is able to lower your risk … It has been routinely consumed in Japanese cultures for hundreds of years. Suzuki Y, Kondo K, Matsumoto Y, et al. Fujita M, Hong K, Ito Y, et al. View abstract. Most research on Serrapeptase points to it’s anti … Thanks. Helps reduce high blood pressure Human volunteers with high blood pressure were given 30 grams of natto extract (equivalent to 7 ounces of natto food), orally for 4 consecutive days. I was taken into the ER with HBP Rate of over 300/165. Report of research: an oral safety study of nattokinase containing food, Natural Super Kinase II: a randomized placebo controlled double-blind study. Drug Dev.Ind.Pharm 2007;33(5):495-503. Please read Nattokinase testimonials and you will find that Nattokinase is helpful for heart problems and it has other health benefits.. Nattokinase … In a study of 79 North Americans, half were given a placebo and the other … They have changed t h e medication several times but they are not working. Angiology 2003;54:531-9. Keep in mind that natural products are not always necessarily safe and dosages can be important. Your email address will not be published. Do not take too much nattokinase if you are taking medications for high blood pressure. Visit the FDA MedWatch website or call 1-800-FDA-1088. Biochem Biophys Res Commun 1993;197:1340-7. Required fields are marked *, Buy 80,000iu Serrapeptase This "thins the blood" and might protect against conditions caused by blood clots such as stroke, heart attack, and others. The LD50 in a rodent study was more than 20,000 FU/kg (more than 1,000 mg/kg). However, it is not known if taking more than two … Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. How do I know? There are hundreds of real people comments left on almost every page on our website, from people suffering with all kinds of ailments, so maybe you can relate and find your own solutions there. A total of 86 participants were included: 44 were randomly assigned to the nattokinase group and 42 were randomly assigned to the control group (2). Nattokinase adds a protective shield to your blood system. High blood pressure is a major medical problem as it leads to heart attacks, strokes, kidney failure, blindness, and dementia. Ages ranged from 20 to 80 years old. Most folks see some results, such as lower blood pressure and lower cholesterol , within 60 to 90 days of starting on the supplement. Surgery: Nattokinase might increase the chance of bleeding too much during or after surgery. You could avoid taking these medications, if you’ve caught the problem early enough. If you take nattokinase along with an anticoagulant like aspirin, coumadin or warfarin, it increases your risk of bleeding, including internal bleeding, says Dr. Ray Sahelian of Los Angeles, author of “Mind Boosters.” In one case, a person taking aspirin to prevent stroke along with 400 milligrams of nattokinase for seven days suffered an acute brain hemorrhage, says Y.Y. (detailed description of each of the ratings). Before taking any kind of alternative medication or supplement, you should speak with your doctor first. If you have any of the following symptoms, you need to see your doctor right away. Five volunteers with high blood pressure each received the extract daily (an oral dose equivalent to 200 g of natto) for four consecutive days. “My blood pressure has usually ranged around 135-145/75-85. There is another proteolytic enzyme that compliments the actions of nattokinase. 6 – https://www.drugs.com/vasodilators.html What other names is Nattokinase known by? I am highly impressed. You can increase it to 4,000 FU daily after 1 to 2 weeks if necessary for greater reduction in blood pressure. In four out of five volunteers, systolic blood pressure … In one study, researchers gave volunteers with high blood pressure 30 grams of natto extract (equivalent to seven ounces of natto) every day for four days. Life Sci 2003;73:1289-98.. View abstract. Nattokinase is POSSIBLY SAFE when taken by mouth as medicine. 86 men and women participated who had stage 1 hypertension, as defined by systolic blood pressure of 130 to 159 mmHg. This silent killer is a common and very serious health … Taking nattokinase along with medications used for lowering high blood pressure might cause your blood pressure to go too low. Your email address will not be published. View abstract. It also helps optimize blood cholesterol. 1 – https://mayoclinic.org/beta-blockers He has suffered with poor circulation (leading to swollen and bruised ankles) since 2004, and has needed to wear compression stockings on both legs. 7-12-2003; Law, D. and Zhang, Z. But, what if I hadn’t (like so many other people)? Nattokinase is LIKELY SAFE when taken by mouth in amounts commonly found in foods. Please kindly download book on nattokinase and serrapeptase to me urgently because I don’t want to be using highpertensive drugs anymore. Taking two doses of a specific product containing nattokinase (Flite Tabs) seems to be safe. 4 – https://mayoclinic.org/calcium-channel-blockers Nattokinase is mostly associated with its fibrinolytic or fibrin dissolving action. Nattokinase is an incredible enzyme supplement that works to protect your cardiovascular system, as well as offering you other health benefits. In 1995, researchers studied the effects of nattokinase on high blood pressure in both animals and humans. Because I'm around…, Serrapeptase for Sore Throat and Mucus Control, Serrapeptase enzyme studies on sinus infections reveal that chronic infections like sinusitis are no match for the…, What is Nattokinase and What Are its Health Benefits, Nattokinase is a serine protease, a highly purified fermented enzyme which has amazing health benefits for the…, How I Continue to Baffle My Doctors With Serrapeptase, Serrapeptase worked it's magic for me again, eating the Hypercalcemia in my kidneys, baffling my doctors. High blood pressure (also called, hypertension), is a preventable disease in most cases. I take two capsule per day – one in the morning and one in the evening (4000 FU’s), which … As you get older, the more you start to take note of the information you see in doctors offices, hospital waiting rooms and even television adverts. Blood Pressure. Hypertens.Res 2008;31(8):1583-1588. And a real positive is that there are no dangers to taking nattokinase, unless you take anti-coagulation medicine. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others. Maruyama M, Sumi H (eds): Effect of natto diet on blood pressure, in Basic and Clinical Aspects of Japanese Traditional Food Natto II. View abstract. The pressure also goes down and I feel amazing. Nattokinase, also known as natto extract (subtilisin NAT or orokinase) is an Thrombolytic effect of nattokinase on a chemically induced thrombosis model in a rat. That’s a dangerously high number considering that high blood pressure puts you directly in the crosshairs of heart disease and elevated stroke risk. Nattokinase can decrease blood clotting. Over the past 3 weeks my HBP has been fluctuating. Invest Ophthalmol.Vis.Sci 2006;47(5):2075-2079. I have been on High blood pressure medication for three weeks. You could just take a daily dose of nattokinase and have piece of mind that you are keeping your blood pressure normal. Nattokinase is a natural component of the soy food natto. The causes and possible symptoms of high blood pressure are listed for you below, but the most alarming thing to me is that once it is diagnosed, your doctor puts you on medication that can actually kill you! Japan Technology Transfer Association (JTTAS), 1998, pp 1–3. There are an increasing number of studies being carried out on nattokinase, because Western prescription medicines are starting to leave a trail ailments, from long term use of (especially) NSAID’s (non steroidal anti inflammatory drugs). But maturity tells me to take note of these things now, because I don’t want to miss any warning signs of potential health concerns. Chang, Y. Y., Liu, J. S., Lai, S. L., Wu, H. S., and Lan, M. Y. Cerebellar hemorrhage provoked by combined use of nattokinase and aspirin in a patient with cerebral microbleeds. NSK-SD® is also safe for those with normal blood pressure and has been found to not effect those with blood pressure … Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. 2. Sumi H, Hamada H, Tsushima H, et al. Am J Health Syst.Pharm 6-15-2006;63(12):1121-1123. You won't find nattokinase in soy foods other than natto, since nattokinase is produced through the specific fermentation process used to make natto. So you can make changes and improvements to your life, and decide for yourself, if those hypertension medicines are for you or if you should use an enzyme therapy like nattokinase, to avoid further health problems. There are bills to pay, families to feed and cloth. You may not need to take those dangerous medications, particularly if you’ve caught the symptoms early enough. But since he was introduced to the miracle enzymes which are discussed in depth throughout this site, nattokinase and serrapeptase, his circulation now flows more freely than every before, and he now has less pain and discomfort. Dosage and Instructions The appropriate … It improves blood viscosity and circulation in general. Suzuki Y, Kondo K, Ichise, H, et al. Serrapeptase is a powerful healer with many health benefits for the heart system, and because it is a strong anti-inflammatory, it can also protect the whole body. In 4 out of 5 volunteers, the systolic blood pressure decreased on average from 173.8 to 154.8. Effects of nattokinase, a pro-fibrinolytic enzyme, on red blood cell aggregation and whole blood viscosity. However, it's not known if this is a big concern. Use with caution. Thanks for your time on our site. Yes, absolutely. And while there are many drugs to reduce high blood pressure… If not, however, you might be prescribed some of this list, to alleviate the symptoms of high blood pressure. Serrapeptase is an enzyme that’s been used in Japan and Europe for decades for pain and inflammation. Chang, lead author for a case report from Taiwan’s Chang Gung … View abstract. For high blood pressure: 2000 formula units of nattokinase have been taken daily for up to 8 weeks. Serrapeptase made my blood pressure, which wasn’t bad, even better. A formulation of nattokinase is reported by the manufacturer to be nonmutagenic in the Ames test using 5 strains of bacteria, as well as in a cell-based chromosomal aberration study conducted in CHL/IU cells.8 It was nontoxic in rodent studies that administered doses up to 1,000 mg/kg/day for up to 90 days. The side effects of prescription blood pressure medication are not to be overlooked. Sitting around all day and not getting enough exercise, added to a bad diet just increases the risk of elevated blood pressure to the point of being dangerous, perhaps even deadly. Urano T, Ihara H, Umemura K, et al. However, we need more research to see if it is effective. BSP, Extrait de Natto, Fermented Soybeans, Haricots de Soja Fermentés, Natto de Soja, Natto Extract, Nattokinasa, NK, Soy Natto, Subtilisin NAT. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others. You owe it to yourself, so protect your livelihood and the future of your family. Lowers Blood Pressure. Are there any interactions with medications? Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. I believe Nattokinase is working. Consequently, blood pressure is lowered. The nattokinase group received one … How…, Mother natures comes to the rescue with serrapeptase, after decades of research into heart health drugs gives…. View abstract. See additional information. View abstract. High blood pressure (hypertension) is split into two categories – primary high blood pressure and secondary high blood pressure. The Profibrinolytic Enzyme Subtilisin NAT Purified from Bacillus subtilis Cleaves and Inactivates Plasminogen Activator InhibitorType 1. See additional information. Combination of 80,000iu serrapeptase, plus 1,600 fu nattokinase (plus other ingredients) for a powerful long term maintenance for a healthy cardiovascular system, lungs and cleansing. Nattokinase is POSSIBLY SAFE when taken by mouth as medicine. We currently have 6 human clinical studies showing NSK-SD’s efficacy in decreasing high blood pressure. I will continue to take it and looking forward to stop these drugs once and for all. In a double blind, controlled study, 86 people were given either nattokinase or a placebo, for eight weeks. Nattokinase might decrease blood pressure in some people. There is a huge list of reasons to look after your heart health, but the following list should help you decide that now is the time to make changes to your lifestyle, if you are concerned about your blood pressure. Experientia 1987;43:1110-1. Dietary supplementation with fermented soybeans suppresses intimal thickening. Nattokinase is an enzyme (a protein that speeds up biochemical reactions) that is extracted from a popular Japanese food called natto. It is also used for pain, fibromyalgia, chronic fatigue syndrome, endometriosis, uterine fibroids, muscle spasms, infertility, cancer, and a vitamin-deficiency disease called beriberi. Clin Hemorheol.Microcirc. The usual dosage is 2,000 – 4,000 FU (Fibrinolytic Units) per day. Only 10% of cases of secondary high blood pressure is caused by other health conditions, or can be attributable to taking medicines for other health conditions, which were designed to help you. Natto is boiled soybeans that have been fermented with a bacterium called Bacillus natto. 44 of the people received a 2,000 FU (Fibrinolysis Units) dosage of nattokinase … We have done our best to ensure all information on this site is accurate, but it should not be used as medical advice in any way. Stop taking it at least 2 weeks before a scheduled surgery. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. All Products. Primary high blood pressure is caused by an array of problems which is usually brought on by the individual themselves. Andy is a health and wellness enthusiast who has a great interest in the cardiovascular system, and more specifically blood circulation. Sumi H, Hamada H, Nakanishi K, Hiratani H. Enchancement of fibrinolytic activity in plasma by oral administration of nattokinase. 7 – https://ncbi.nlm.nih.gov/pubmed/18971533. The usual prescription drugs for high blood pressure (hypertension) are: And in more severe cases of high blood pressure, your doctor may prescribe: These lists are a consortium of drugs that could eventually end up causing your body further damage, with long term use. You can virtually shut down the onset of hypertension, and also prevent any further serious cardiovascular diseases from occurring, potentially saving your life. home >  vitamins, herbs, dietary supplements a-z listnattokinase. Nattokinase Heart Health is a website set up by a wellness enthusiast, NOT a medical professional. Please use the form on this page to sign up to our newsletter, from there your book can be downloaded. I understand now, because of my younger attitude towards these types of things, how in today’s society there is so much disease. Biol Pharm Bull 1995;18:1387-91. 2 – https://en.wikipedia.org/Renin_inhibitor Pais, E., Alexy, T., Holsworth, R. E., Jr., and Meiselman, H. J. My guess is that I would be in pretty poor shape today, and part of the Western civilization obesity epidemic. View abstract. These health problems are diabetes, kidney disease, hormonal imbalances or taking anti-inflammatory drugs, or in women, the contraceptive pill. View abstract. 3 – https://bupa.co.uk/health/ace-inhibitors Diastolic blood pressure … Taking two doses of a specific product containing nattokinase (Flite Tabs) seems to be safe. Other studies show that nattokinase may help lower blood pressure. If you’re already on high blood pressure or statin drugs, nattokinase … The recommended dosage for nattokinase is one capsule in the morning, one capsule in the afternoon and two capsules at bedtime. Not a nice thought. View abstract. Kim, J. Y., Gum, S. N., Paik, J. K., Lim, H. H., Kim, K. C., Ogasawara, K., Inoue, K., Park, S., Jang, Y., and Lee, J. H. Effects of nattokinase on blood pressure: a randomized, controlled trial. Stabilization and target delivery of Nattokinase using compression coating. Purification and characterization of a strong fibrinolytic enzyme (nattokinase) in the vegetable cheese natto, a popular soybean fermented food in Japan. Natto has been used as a folk remedy for diseases of the heart and circulatory system (cardiovascular disease) for hundreds of years. On average, systolic blood pressure … It is also possibly effective in reducing blood pressure. Please note that all information and content on this site, including articles, videos and articles linked to and from this site are for information purposes only. Even worse, some people try to exist in a ‘micro-second world’ focusing on their career and the daily tasks of their job, on top of pursuing poor lifestyle habits. Since nattokinase is … Takano, A., Hirata, A., Ogasawara, K., Sagara, N., Inomata, Y., Kawaji, T., and Tanihara, H. Posterior vitreous detachment induced by nattokinase (subtilisin NAT): a novel enzyme for pharmacologic vitreolysis. … other studies show that nattokinase may help lower blood pressure at a level... Also POSSIBLY effective in reducing blood pressure can increase it to 4,000 FU daily after 1 to 2 weeks necessary. Not enough scientific information to determine an appropriate range of doses for nattokinase one... Average from 173.8 to 154.8 2021 by RxList Inc. RxList does not provide advice... Wasn ’ t bad, even better problems are diabetes, kidney disease, hormonal imbalances or taking drugs... Inc. RxList does not provide medical advice, diagnosis or treatment unless you anti-coagulation..., which wasn ’ t bad, even better so many other people ) on pressure! Doctor right away which could safely do the job of most of the five,. And serrapeptase to me urgently because I don ’ t bad, even better my blood to... 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You might be prescribed some of this list, to alleviate the early. ):495-503 supplement, you need to see your doctor first could just take a daily dose nattokinase! Marked *, Buy 80,000iu serrapeptase Buy 250,000iu serrapeptase all Products in fact, just reading about some of list. For nattokinase is a big concern negative side effects of nattokinase … it improves blood viscosity and in... Follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using 2018 RxList! Two doses of a specific product containing nattokinase ( Flite Tabs ) seems be... Taken into the ER with HBP Rate of over 300/165 Y, Kondo K, Matsumoto Y, K! The afternoon and two capsules at bedtime 5 ):5 pp 1–3 Japanese cultures for hundreds of years Effectiveness!, Matsumoto Y, et al healthcare professional before using D Deficiency How! You can get the most vitamin C from ________________ Dev.Ind.Pharm 2007 ; (. 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