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2000;20(1):38-41. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. View abstract. Ann Clin Biochem 2007;44(Pt 4):397-399. View abstract. View abstract. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. Licorice is an herb that grows in parts of Europe and Asia. View abstract. Other conditions. Deglycyrrhizinated liquorice in duodenal ulcer. Licorice roots can be consumed directly to get relief from cough and sore throat. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. Bai, Y. S., Zhou, C. Y., and Wang, J. Q. Electronic Code of Federal Regulations. Guo TL, Zhou XW. van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Peony root might decrease the amount of phenytoin in the body. Br J Clin Pract 1972;26(12):563-566. Licorice, tobacco chewing, and hypertension. [Peony tincture in the complex treatment of allergic dermatoses]. J Clin Hypertens (Greenwich) 2016;18(2):159-60. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. Nishioka, K. and Seguchi, T. Contact allergy due to oil-soluble licorice extracts in cosmetic products. Licorice might increase blood pressure. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. View abstract. Riv Patol Nerv Ment 1983;104(4):179-183. Hinoshita F, Ogura Y, Suzuki Y, et al. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. 2020;50:102401. View abstract. The anti-estrogenic action of beta-glycyrrhetinic acid. Deglycyrrhizinated liquorice in aphthous ulcers. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. J Clin Psychopharmacol 2016;36(6):572-9. View abstract. Some medications are moved in and out of cells by pumps. Read more. CJEM 2010;12(3):224-225. Cureus 2021;13(7):e16454. J Clin Psychopharmacol 1997;17(3):234-235. Int J Dermatol 1999;38:387-92 . This might increase the effects and side effects of methotrexate. View abstract. Endocrinol Jpn 1991;38(2):167-174. Black licorice contains a compound that comes from licorice root that can lower your potassium levels. View abstract. BMJ Case Rep 2012;2012. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. View abstract. Eyi, E. G., Engin-Ustun, Y., Kaba, M., and Mollamahmutoglu, L. Ankaferd blood stopper in episiotomy repair. Isr J Dent Sci 1989;2(3):153-157. This can be severe. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Mouthwash Containing Glycyrrhiza uralensis Extract for Preventing Dental Caries. Clin Med (Lond) 2017;17(1):43-5. Kim YR, Nam SH. J Am Coll.Nutr 2007;26(3):209-218. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. View abstract. $9.44 $ 9. Sigurjonsdottir, H. A., Manhem, K., Axelson, M., and Wallerstedt, S. Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. View abstract. Ed. Anon. View abstract. Lancet 2003;361:2045-6.. View abstract. 2013 Jun;22(2):173-8. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. Hypertension and the cortisol-cortisone shuttle. Back to the Blog. Pak J Med Sci 2022;38(1):271-275. View abstract. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. View abstract. Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . J Clin Periodontol 1991;18(3):210-212. Select a condition to view a list of vitamins. Badr, A. E., Omar, N., and Badria, F. A. A., Keller, W. J., Pereira, M. A., and Kinghorn, A. D. Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). View abstract. Medicine (Baltimore) 2019;98(35):e16601. View abstract. View abstract. Some birth control pills contain estrogen. Am.J Chin Med 2004;32(4):569-578. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. An Bras Dermatol 2010;85(5):613-620. View abstract. Indian J Med Res 1993;98:69-74. Unfortunately, there is not much scientific evidence around the use of Licorice in Hirsutism, and more studies are needed to prove if it's effective in hirsutism or not. View abstract. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. View abstract. Taking licorice and loop diuretics together might make potassium levels drop too low. J Ethnopharmacol 2011;135(1):162-72. Nutrition 2002;18(3):268-273. How Much Is Too Much? Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. Curr.Pharm.Des 2010;16(26):2935-2947. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Luo, Y. G., Liu, Y. Q., and Hu, J. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. 2010 Nov;35(10):1587-93. Biol Pharm Bull 1998;21:1277-81. View abstract. View abstract. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. Antiviral Res 1987;7(2):99-107. View abstract. The 54-year-old man was in a fast food . View abstract. All rights reserved. Rosenblat, M. and Aviram, M. Paraoxonases role in the prevention of cardiovascular diseases. View abstract. Scand.J Gastroenterol. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . 2019;35:329-41. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Drug Metab Dispos 2015;43(7):1147-53. White Peony is technically named Peonia lactiflora, and in Chinese, it is named Bai Shao. J Assoc Physicians India 1989;37(10):647. J Med Liban 2012;60(2):117-119. Licorice that has had this substance removed (called DGL for deglycyrrhizinated licorice) may not have the same degree of side effects. View abstract. View abstract. Eagon PK, Elm MS, Hunter DS, et al. Plant Description. J Ethnopharmacol 2004;94:339-44. . View abstract. View abstract. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). View abstract. Am J Respir.Cell Mol.Biol. View abstract. View abstract. View abstract. Pharmazie 2010;65(8):624-8. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Licorice has been used as a medicinal plant from 2.500 years. This Halloween, you'll want to stay vigilant about the candy . Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Iran J Pharm Res. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. Food Chem Toxicol 1993;31:303-12. A Rutgers expert discusses how eating black licorice can affect your health. View abstract. Another type of licorice, called DGL or deglycyrrhizinated licorice, does not seem to have the same side effects and is sometimes used to treat peptic ulcers, canker sores, and reflux (GERD). View abstract. View abstract. Not too many side effects of peony tea that we need to worry about. . Information from this source is evidence-based and objective, and without commercial influence. J Contemp.Dent Pract. Biol Pharm Bull 2007;30(11):2191-2195. For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Zhonghua Yi Xue Za Zhi 1983;63:477-81. View abstract. Liang, R., Chen, M. R., and Xu, X. View abstract. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. This could change the effects and side effects of these medications. Can J Cardiol 2009;25(10):e357-e358. Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . 2000;19(8):434-439. For people who already have high blood pressure or heart or kidney disease, as little as 5 g/day can cause these side effects. Health Care Women Int. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. However, when Angelica Sinensis was tested in combination with products containing other substances, its activity was reduced. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. View abstract. View abstract. View abstract. Kraus SD, Kaminskis A. View abstract. Therapeutic Research Faculty 2020. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. I like herbal and fuit teas and a particular favourite of mine contains liquorice. Postgrad Med 2017;129(3):329-31. A. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Neth J Med 2005;63:119-20. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. But the potential side effects are real enough. J Intern Med 1999;245:307-10. Clin Rheumatol. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. Licorice, tobacco chewing, and hypertension. October 15, 2021. View abstract. View abstract. Contact Dermatitis 1989; 20:152-3.. View abstract. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. Westman EC, Guthrie GP. Chatterjee, N., Domoto-Reilly, K., Fecci, P. E., Schwamm, L. H., and Singhal, A. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. View abstract. Lipids Health Dis 2011;10:29. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Kumada T, et al. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Int J Nurs Stud 2016;63:9-17. View abstract. View abstract. Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. All rights reserved. View abstract. Sheehan M, Rustin MHA, Atherton DJ, et al. View abstract. Z Gastroenterol 2001;39(7):511-7. Phytother Res 2008;22(6):709-724. 2009;14(1):64-65. View abstract. View abstract. View abstract. Evid Based Complement Alternat Med 2016;2016:8292486. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Zhang W, Dai SM. Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. J Cancer Res Ther. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. J Clin Anesth 2019;54:25-32. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. 2010;33(2):321-324. Erratum in: Clin Rheumatol. Kase Y, Saitoh K, Ishige A, et al. View abstract. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Antiviral Res 1989;11(5-6):255-261. Kroes, B. H., Beukelman, C. J., van den Berg, A. J., Wolbink, G. J., van Dijk, H., and Labadie, R. P. Inhibition of human complement by beta-glycyrrhetinic acid. View abstract. Lee, I. T., Lee, W. J., Tsai, C. M., Su, I. J., Yen, H. T., and Sheu, W. H. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. Anesth Analg 2009;109(1):77-81. View abstract. View abstract. J Hum Hypertens 2001;15:549-52. When eaten in large quantities, black licorice can cause serious health issues. Antiviral Res 2003;59(1):41-47. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Nutr 2001;131:1471-8. Luper, S. A review of plants used in the treatment of liver disease: part two. Antiviral Res 1987;7(3):127-137. Fugh-Berman, A. Herb-drug interactions. Brouwers, A. J. and van der, Meulen J. Oral Dis 2012;18(1):32-39. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. Eur Neurol 1992;32(1):44-51. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. (Glycyrrhiza glabra), it performs better, especially for relaxing muscles, reducing painful menstruation, as well as lowering serum and free testosterone levels in women with PCOS. Amaryan G, Astvatsatryan V, Gabrielyan E, et al. The dose of your warfarin might need to be changed. View abstract. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. Lancet 2000;355(9198):134-138. 10. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Most clinical trials have found that when Peony is combined with Licorice Rt. Nat Prod Res 2007;21(14):1234-1241. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Ito A, Hayashi N, Katayama K, and et al. View abstract. View abstract. Taking too much licorice can cause high blood pressure. Life Sci 1993;53(5):PL63-8. Immunopharmacology 1999;41(3):169-181. J Dermatolog Treat 2003;14(3):153-157. Gut 1978;19(9):779-782. J Gastroenterol 1996;31(5):691-695. View abstract. Inflammopharmacology 2022;30(2):477-486. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. 2020;2020:3727682. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Dying for a cup of tea. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. mentioned adverse effects and recurrence rates. View abstract. Z., Zhang, Y. Licorice might decrease the effects of warfarin. Taking peony along with birth control pills might increase the risk of side effects. In some cases, this might change the effects and side effects of a medication. View abstract. Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Peony (Paeonia spp). Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. View abstract. View abstract. Yu C, Fan X, Li Z, Liu X, Wang G. Efficacy and safety of total glucosides of paeony combined with acitretin in the treatment of moderate-to-severe plaque psoriasis: a double-blind, randomised, placebo-controlled trial. Brasseur, A. and Ducobu, J. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. View abstract. Astragalus may be safe when used orally and appropriately. Benge E, Shah P, Yamaguchi L, Josef V. Trick or Treat? Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. Li C, Wang ZB. View abstract. View abstract. Man SC, Li XB, Wang HH, et al. Wang W, Tian DD, Zheng B, et al. Tewari SN, Wilson AK. Anesth Analg. View abstract. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. View abstract. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. View abstract. Sigurjonsdottir HA, Franzson L, Manhem K, et al. View abstract. Am J Chin Med 2001;29(3-4):459-467. View abstract. Diane Calello, executive medical director of the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, discusses safe . Some medications are changed and broken down by the liver. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Asia Pac.J Clin Nutr 2008;17(1):17-22. View abstract. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Moreover, it will be necessary to check for recurrence . N Engl J Med 1999;341:1158. PC-SPES, a dietary supplement for the treatment of hormone-refractory prostate cancer. Murck H, Lehr L, Hahn J, Braunisch MC, Jezova D, Zavorotnyy M. Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression-A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target. View abstract. Anonymous. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. An open study of 100 women with uterine fibroids showed that peony reduced the size of . Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Crit Care 2011;15(1):R64. 2019;38(3):657-64. View abstract. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. [A plant extract and its modified preparation in functional dyspepsia. Ital.J Neurol.Sci 1997;18(4):217-220. Zhang YD, Lorenzo B, Reidenberg MM. Hum Exp Toxicol 2012;31(12):1295-1298. View abstract. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. View abstract. Yang F, Qi X, Du Y, et al. View abstract. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. Low doses of liquorice can induce hypertension encephalopathy. Liquorice and hypertension. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Life Sci 9-27-2002;71(19):2267-2277. View abstract. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. View abstract. View abstract. 2017 Sep;31(9):1330-1340. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. J Clin Psychopharmacol 1997;17(3):234-235. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. Other side effects of licorice use include . Zhong Xi Yi Jie He Za Zhi 1991;11(3):150-2, 133. Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Taking peony along with estrogen might increase the effects and side effects from estrogen. Qraa Advanced Lacto Dark Underarm Whitening Cream Product Claims Qraa underarm whitening cream claims to lighten dark underarms by reducing melanin from the skin in the area. Akamatsu, H., Komura, J., Asada, Y., and Niwa, Y. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Epilepsy Res 2021;176:106735. Some sources claim that it's contraindicated during pregnancy . There is only one reminder that peony tea contains caffeine. Peters, M. C., Tallman, J. (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women. Neth J Med 2005;63:146-8. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. Side effects of peony tea! Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. 2003;84(1):85-89. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. Kim, H. J., Chang, E. J., Bae, S. J., Shim, S. M., Park, H. D., Rhee, C. H., Park, J. H., and Choi, S. W. Cytotoxic and antimutagenic stilbenes from seeds of Paeonia lactiflora. Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Mol Cell Endocrinol. View abstract. Cinatl J, Morgenstern B, Bauer G, et al. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. In 1977, researchers reported the case of a 58-year-old woman who was eating a whopping 1.8 kilograms (about 63.5 ounces) of black licorice per week and went into cardiac arrest. Xu Y, Li X, Chen T, et al. Chen LC, Chou MH, Lin MF, Yang LL. View abstract. J Pharm Pharmacol 2003;55:1275-82. A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating microbiota and reducing inflammation . 2014 Jun;20(6):516-20. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy. [Severe hypokalemia after holidays return]. Hypertension encephalopathy after liquorice ingestion.